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| Place of Origin: | Wuhan, China |
| Brand Name: | Vanz |
| Certification: | ISO9001 |
| Model Number: | TIMTEC-BB SBB000930 |
| Minimum Order Quantity: | 100g |
|---|---|
| Price: | USD 1-100/gram |
| Packaging Details: | 10g,100g, 1kg Aluminum Foil bag/25kg drum/ Customiszed. |
| Delivery Time: | 1-7days upon down payment. |
| Payment Terms: | L/C, T/T, Western Union, MoneyGram |
| Supply Ability: | 500 Kg/Month |
| Product Name: | 7,8-DIHYDROXYFLAVONE | MF: | C15H10O4 |
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| MW: | 254.24 | CAS: | 38183-03-8 |
| Appearance: | Yellow Solid | Synonyms: | TIMTEC-BB SBB000930;7,8-DIHYDROXYFLAVONE;7,8-Dihydroxyf |
| High Light: | Pharma Raw Materials,medicine raw material |
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7,8-DIHYDROXYFLAVONE Yellow powder TIMTEC-BB SBB000930 Lowering blood pressure
Product introduction:
7,8-Dihydroxyflavone (7,8-DHF) is a naturally-occurring flavone found in Godmania aesculifolia, Tridax procumbens, and primula tree leaves. It has been found to act as a potent and selective small-moleculeagonist of the TrkB receptor (Kd ≈ 320 nM), the main signaling receptor of brain-derived neurotrophic factor(BDNF).7,8-DHF is both orally-bioavailable and able to penetrate the blood-brain-barrier.
7,8-Dihydroxyflavone is disubstituted flavone that acts as a small-molecule TrkB agonist. 7,8-Dihydroxyflavone has been shown to reverse memory deficits and BACE1 elevation in a mouse model of Alzheim er's disease. 7,8-Dihydroxyflavone may also provide a therapeutic option in the treatment of other neorological disorders such as Rett syndrome and PTSD.
Specification:
| Product Name: | 7,8-DIHYDROXYFLAVONE |
| Synonyms: | TIMTEC-BB SBB000930;7,8-DIHYDROXYFLAVONE;7,8-Dihydroxyflavone hydrate |
| CAS: | 38183-03-8 |
| MF: | C15H10O4 |
| MW: | 254.24 |
| EINECS: | 253-812-4 |
| Product Categories: | Di-substituted Flavones;Biochemistry;Flavonoids;Inhibitors |
| Mol File: | 38183-03-8.mol |
| mp | 243-246°C |
| storage temp. | Store at +4°C |
| CAS DataBase Reference | 38183-03-8(CAS DataBase Reference) |
| Chemical Properties | Yellow Solid |
| Biological Activity | Tyrosine kinase receptor B (TrkB) agonist that binds to the extracellular domain of the receptor (K d = 320 nM). Inhibits glutamate-triggered apoptosis in hippocampal neurons in vitro and in vivo . |
Structural formula:
FAQ:
Q1: Are you a manufacturer?
A: Yes, We manufacture bulk products in our factory located in Jiayu, Hubei, and produce small quantity and customer synthesis products in our lab located in Wuhan.
Q2: Do you have stock?
A: We understand most customers prefer stock, so we'll try to keep stock for most products. However, for some rare products, we won't keep stock and it needs time to synthesize.
Q3: What certificates and documents do you offer?
A: Some technical paperwork is available, such as COA, HNMR, HPLC, LC-MS etc.
Q4: Why should I choose you?
A: Powerful technical support-come from our highly skilled & fully experienced staff, working in chemical industry for over 5 years, in average.
Strict quality control-comes form our sophisticated management system.
Professional and warm sales team-since we believe we can only win via our hard work in a competitive world
Quick response and excellent presale and after sale service-since we believe our customers deserve all the best service
Q5: Can I get best price from you?
A: Of course. We don't chase excessive profits and always try tp give best offer. If you are good at bargaining, you can also enjoy fun of bargaining. Just don't make it too hard!
Q6: How should I pay?
A: We accept all kinds of payment ways. such as alibaba trade asssurance, T/T, West union, Paypal.
Q7: Do you provide free sample?
A: Yes, we can provide free sample if we have in stock, just need you to cover the delivery cost.
Contact Person: Ms. Wendy Wang
Tel: +86 15927784577
Fax: 86-27-84492310
