Place of Origin: | China |
Brand Name: | Vanz |
Certification: | ISO9001 |
Model Number: | 231277-92-2 |
Minimum Order Quantity: | 1g |
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Packaging Details: | bags or drum |
Delivery Time: | 3-5 days |
Payment Terms: | T/T, Western Union, MoneyGram |
Supply Ability: | 2kg per month |
Name: | Lapatinib / Lapatinib Ditosylate | CAS: | 231277-92-2 |
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Appearance: | Yellow Fine Powder | COA: | Available |
Assay: | 99%min | Stock: | Available |
High Light: | active pharmaceuticals ingredients,active pharma ingredients |
Api Pharmaceutical Raw Material Lapatinib Ditosylate CAS 231277-92-2
Introduction
Lapatinib (INN), used in the form of lapatinib ditosylate, (USAN) (Tykerb/Tyverb, GSK) is an orally active drug for breast cancer and other solid tumours.[1] It is a dual tyrosine kinase inhibitor which interrupts the HER2/neu and epidermal growth factor receptor (EGFR) pathways.[2] It is used in combination therapy for HER2-positive breast cancer. It is used for the treatment of patients with advanced or metastatic breast cancer whose tumors overexpress HER2 (ErbB2).
Synonym: | lapatinib;n-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[(2-methylsulfonylethylamino)methyl]-2-furyl]quinazolin-4-amine;4-Quinazolinamine, N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-;Lapatinib(TINIBS);N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[(2-methylsulfonylethylamino)methyl]-2-furyl]quinazolin-4-amine;Lapatinib Base N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-4-Quinazolinamine;N-(3-chloro-4-((3-fluorobenzyl)oxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)furan-2-yl)quinazolin-4-amine;4-[[3-Chloro-4-(3-fluorobenzyloxy)phenyl]amino]-6-[5-[[(2-methanesulfonylethyl)amino]methyl]furan-2-yl]quinazoline |
Application: | An inhibitor of Src family kinases, including c-Abl and Bcr-Abl tyrosine kinase activity |
CAS Number: | 231277-92-2 |
Purity: | ≥99% |
Molecular Weight: | 581.0575432 |
Molecular Formula: | C29H26ClFN4O4S |
Status
Related Intermediate
Lapatinib ditosylate | 388082-78-8 |
4-Chloro-6-iodoquinazoline | 98556-31-1 |
2-Formylfuran-5-boronic acid | 27329-70-0 |
2-Aminoethylmethylsulfone hydrochloride | 104458-24-4 |
N-[3-Chloro-4-(3-fluorobenzyloxy) phenyl]-6-iodoquinazolin-4-amine |
231278-20-9 |
FAQ
Q1: Are you a manufacturer ?
A: Yes, We manufacture bulk products in our factory located in Jiayu, Hubei, and produce small quantity and customer synthesis products in our lab located in Wuhan. But we also do some trading business.
Q2: What`s your delivery
A: We send goods in 3 working day after receiving your payment by DHL, FEDEX, TNT, EMS, AIR OR SEA as you request, usually you can find shipping details in 3 to 5 working days after your payment.
Q3: What certificates and documents do you offer?
A: Some technical paperwork is available, such as COA, HNMR, HPLC, LC-MS etc.
Q4: Why should I choose you?
A: Factory supply with the most compatitive price and high quality!!!
Q5: Can I get best price from you?
A: Of course. We don't chase excessive profits and always try tp give best offer. If you are good at bargaining, you can also enjoy fun of bargaining. Just don't make it too hard!
Q6: How should I pay?
A: We accept all kinds of payment ways. such as alibaba trade asssurance, T/T, West Union, Money Gram.
Q7: Do you provide free sample?
A: We can provide free sample of some chemicals and you just need you to cover the delivery cost.
Contact Person: Ms. Wendy Wang
Tel: +86 15927784577
Fax: 86-27-84492310