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Hubei Vanz Pharm Co.,ltd
Hubei Vanz Pharm Co.,ltd

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302964-24-5 Dasatinib Intermediate Pharmaceutical Active Ingredients

302964-24-5 Dasatinib Intermediate Pharmaceutical Active Ingredients

  • 302964-24-5 Dasatinib Intermediate Pharmaceutical Active Ingredients
  • 302964-24-5 Dasatinib Intermediate Pharmaceutical Active Ingredients
302964-24-5 Dasatinib Intermediate Pharmaceutical Active Ingredients
Product Details:
Place of Origin: China
Brand Name: vanz
Certification: ISO9001
Model Number: 302964-24-5
Payment & Shipping Terms:
Minimum Order Quantity: 1kg
Price: USD550-600 Per kg
Packaging Details: 1kg net/foil-alum bag, 25kg/drum
Delivery Time: 3-7 days
Payment Terms: T/T, Western Union, MoneyGram
Supply Ability: 150kg per month
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Detailed Product Description
Appearance: Off-white Powder CAS: 302964-24-5
COA: Available Stock: Available
Synonyms: 2-AMINO-N-(2-CHLORO-6-METHYLPHENYL)THIAZOLE-5-CARBOXAMIDE;2-AMino-N-(2-chloro-6-Methylphenyl)thiazole-5-carb;2-aMino-N-(2-chloro-6-Methylphenyl)-1,3-thiazole-5-carboxaMide;dasatinib InterMediate;Dasatinib IMpurity 2;2-AMino-N-(2-chloro-6-Methylphenyl)thiaz Application: Intermediate Of API Dasatinib
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302964-24-5 Dasatinib Intermediate Pharmaceutical Active Ingredients

 

Introduction

 

2-Amino-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide is one kind of intermediate of dasatinib.

 

Basic Information

 

2-Amino-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide
Product Name: 2-Amino-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide
Synonyms: 2-AMINO-N-(2-CHLORO-6-METHYLPHENYL)THIAZOLE-5-CARBOXAMIDE;2-AMino-N-(2-chloro-6-Methylphenyl)thiazole-5-carb;2-aMino-N-(2-chloro-6-Methylphenyl)-1,3-thiazole-5-carboxaMide;dasatinib interMediate;Dasatinib IMpurity 2;2-AMino-N-(2-chloro-6-Methylphenyl)thiazole-5-carboxiMide);2-Amino-5-[(2-chloro-6-methylphenyl)carbamoyl]-1,3-thiazole, 2-Amino-5-[(6-chloro-o-tolyl)carbamoyl]-1,3-thiazole
CAS: 302964-24-5
MF: C11H10ClN3OS
MW: 267.73
EINECS:  
Product Categories: Dasatinib;API intermediates
Mol File:

302964-24-5.mol

 

About Dasatinib

 

Dasatinib, previously known as BMS-354825, is a cancer drug produced by Bristol-Myers Squibb and sold under the trade name Sprycel. Dasatinib is an oral Bcr-Abl tyrosine kinase inhibitor (inhibits the "Philadelphia chromosome") and Src family tyrosine kinase inhibitor approved for first line use in patients with chronic myelogenous leukemia (CML) and Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL). It is being evaluated for use in numerous other cancers, including advanced prostate cancer.

 

Item Acceptance criteria Result 
Appearance Off- white to pale yellow powder Off-white powder
Identification IR absorption spectrum of sample should be consistent with spectrum of standard Conforms
Water No more than0.70% 0.50%
Residue on ignition No more than 0.50% 0.17%
Related substance

Thuourea no more than 0.07%

Individual impurity no more than 0.20%

Total impurities no more than 0.50%%

0.004%

0.06%

0.15%

Assay 98.0%-102.0% (On anhydrous basis) 99.7%

 

In a Phase I dose escalation study published in June 2006, dasatinib was tested in patients who were resistant to or who could not tolerate imatinib. Complete hematological responses were seen in 37 of 40 patients with chronic-phase CML. Major hematologic responses were seen in 31 of 44 patients with accelerated-phase CML, CML in blast crisis, or Ph+ ALL.

 

FAQ

 

1. Are you a manufacturer ?
Yes, We manufacture bulk products in our factory located in Jiayu, Hubei, and produce small quantity and customer synthesis products in our lab located in Wuhan. But we also do some trading business

2. How to confirm the product quality before placing orders ?
a. We will offer you our products specification standard to you, and we test every batch of our product by HPLC, UV, GC and TLC and etc. We also cooperate with independent third party lab such as SGS,PONY etc.
b. Free samples of some products can be sent, only need to pay the shipping cost or arrange a courier to us and take the samples.
c. Send us your products specifications and requests, we will produce for you.

3. How to make order & payment ?
a. Proforma invoice will be sent after your confirmation of the order, or You can order from Alibaba ESCOW(SECURE PAYMENT), Trade Assurance
b. We can accept payment by T/T, Western Union, Escrow, ,Trade Assurance, L/C.

4. How to pack and storage ?
a. Packing: 1kg/Aluminum foil bag with Carton outside.
25kg/Fiber drum with double PE bags inside.
b. Storage: Store in cool & dry place, keep away from strong light and heat.

5. How to ship and delivery ?
a. Transit could be DHL,UPS,TNT, FEDEX, EMS. For mass orders, it will be delivered by air or sea.
b. Depending on your location,
For small order, please expect 5-7 days by DHL,UPS,TNT, FEDEX, EMS.
For mass order, please allow 5-8 days by Air, 20-35 days by Sea.

6. Our return service policy
We offer an unconditional,full money back guarantee. if you are not 100% satisfied with our products ,return all goods back to us within 60 day and we will fully refund your money. No questions asked.

 

302964-24-5 Dasatinib Intermediate Pharmaceutical Active Ingredients 0

Contact Details
Hubei Vanz Pharm Co.,ltd

Contact Person: Ms. Wendy Wang

Tel: +86 15927784577

Fax: 86-27-84492310

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Hubei Vanz Pharm Co.,ltd
Room 2114, Jingkai future town, Longyang Road, Wuhan Economic & Technological Development District, Wuhan City, Hubei , China
Tel:86-27-84492310
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