Flibanserin Hydrochloride 99% Medicine Intermediate CAS 147359-76-0

Flibanserin Hydrochloride 99% Medicine Intermediate CAS 147359-76-0

Introduction:

Flibanserin is a medication for the treatment of pre-menopausal women with hypoactive sexual desire disorder (HSDD). The medication increases the number of satisfying sexual events per month by about one half over placebo from a starting point of about two to three.

Description:

Mechanism of Action:

Flibansetrin has high affinity for serotonin receptors in the brain: it acts as an agonist on 5-HT1A and an antagonist on 5-HT2A. In vivo, flibanserin binds equally to 5-HT1A and 5-HT2A receptors. However, under higher levels of brain 5-HT (i.e., under stress), flibanserin may occupy 5-HT2A receptors in higher proportion than 5-HT(1A) receptors. It may also moderately antagonize D4 (dopamine) receptors and 5-HT2B and 5-HTB2C. Its action on neurotransmitter receptors may contribute to reduction in serotonin levels and increase in dopamine and norepinephrine levels, all of which may play part in reward processing.

Packing:

aluminum foil bag, cardboard drum, customize

Specification:

10g-25kg per packing unit

Shipment method:

by courier, by air or by sea

Packing details:

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