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Hubei Vanz Pharm Co.,ltd
Hubei Vanz Pharm Co.,ltd

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3382-63-6 Pharmaceutical Intermediates Ezetimibe Intermediate Cholesterol Absorption Inhibitor

3382-63-6 Pharmaceutical Intermediates Ezetimibe Intermediate Cholesterol Absorption Inhibitor

  • 3382-63-6 Pharmaceutical Intermediates Ezetimibe Intermediate Cholesterol Absorption Inhibitor
  • 3382-63-6 Pharmaceutical Intermediates Ezetimibe Intermediate Cholesterol Absorption Inhibitor
3382-63-6 Pharmaceutical Intermediates Ezetimibe Intermediate Cholesterol Absorption Inhibitor
Product Details:
Place of Origin: China
Brand Name: Vanz
Model Number: Ezetimibe Intermediate 1
Payment & Shipping Terms:
Minimum Order Quantity: As custom's requirment
Packaging Details: as custom's requirment
Delivery Time: within 7 working days
Payment Terms: T/T, Western Union, MoneyGram
Supply Ability: 20 kg per month
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Detailed Product Description
Color: Yellow Package: Drum
Purity: 99 Test: HPLC
Usage: Ezetimibe Intermediate MF: C13H10FNO
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3382-63-6 Pharmaceutical Intermediates Ezetimibe Intermediate Cholesterol Absorption Inhibitor


Product Info :

 

Molecular Formula: C13H10FNO
CAS Registry Number: 3382-63-6
Usage:An intermediate of Ezetimibe .

 

About Ezetimibe :
Ezetimibe,is the first selective cholesterol absorption inhibitor, the product is first approved by the US FDA listed as selective cholesterol absorption inhibitor class of drugs.

Ezetimibe is a new selective cholesterol absorption inhibitor, it is also the first selective inhibitor of intestinal cholesterol absorption, and its mechanism of action is different from other lipid-lowering agents (such as: statins, bile acid sequestrants, phenoxy acid derivative thereof cattle and plant sterol ester compound), the product ,through binding with the intestinal brush border membrane vesicle membrane protein (relative molecular mass 145X103), inhibits intestinal absorption of cholesterol which is from diet and transported to the intestine via the bile tract , reduces serum and liver cholesterol. Different from acid chelating agent ,ezetimibe does not affect cholesterol esters, other steroids (such as bezoar acid), triglycerides and fat-soluble vitamin absorption. Its pharmacological effects have nothing to do with acetyl coenzyme A- cholesterol acetyltransferase (ACAT) inhibiting and LDL receptors (scavenger receptor) expression . After being absorbed in the liver , ezetimibe combined with glucuronic acid by enterohepatic circulation,is almost specifically targeting to the small intestine mucosa. It can be used alone or in combination with HMG-CoA reductase inhibitors (statins) jointly applied to the treatment of primary (heterozygous familial and non-familial) hypercholesterolemia, homozygous familial hypercholesterolemia (HoFH) homozygous sitosterol hyperlipidemia (hyperlipidemia or phytosterols).

 

Packaging:


(1) 10g/100g/500g/1kg, packaged by Aluminum foil bag.
(2) Customized package.

Chemical Properties:

Appearance

 Off white powder

Molecular Weight 215.22
Molecular Structure  3382-63-6 Pharmaceutical Intermediates Ezetimibe Intermediate Cholesterol Absorption Inhibitor 0

 

Safety Information:

hazard Codes Xi
Risk Statements 41
Safety Statements 26-39

 

 

3382-63-6 Pharmaceutical Intermediates Ezetimibe Intermediate Cholesterol Absorption Inhibitor 1

3382-63-6 Pharmaceutical Intermediates Ezetimibe Intermediate Cholesterol Absorption Inhibitor 2


FAQ:
Q1: Are you a manufacturer?
A: Yes, We manufacture bulk products in our factory located in Jiayu, Hubei, and produce small quantity and customer synthesis products in our lab located in Wuhan.
Q2: Do you have stock?
A: We understand most customers prefer stock, so we'll try to keep stock for most products. However, for some rare products, we won't keep stock and it needs time to synthesize.
Q3: What certificates and documents do you offer?
A: Some technical paperwork is available, such as COA, HNMR, HPLC, LC-MS etc.
Q4: Why should I choose you?
A: Powerful technical support-come from our highly skilled & fully experienced staff, working in chemical industry for over 5 years, in average.
Strict quality control-comes form our sophisticated management system.
Professional and warm sales team-since we believe we can only win via our hard work in a competitive world
Quick response and excellent presale and after sale service-since we believe our customers deserve all the best service
Q5: Can I get best price from you?
A: Of course. We don't chase excessive profits and always try tp give best offer. If you are good at bargaining, you can also enjoy fun of bargaining. Just don't make it too hard!
Q6: How should I pay?
A: We accept all kinds of payment ways. such as alibaba trade asssurance, T/T, West union, Paypal.
Q7: Do you provide free sample?
A: Yes, we can provide free sample if we have in stock, just need you to cover the delivery cost.

Contact Details
Hubei Vanz Pharm Co.,ltd

Contact Person: Ms. Wendy Wang

Tel: +86 15927784577

Fax: 86-27-84492310

Send your inquiry directly to us
Hubei Vanz Pharm Co.,ltd
Room 2114, Jingkai future town, Longyang Road, Wuhan Economic & Technological Development District, Wuhan City, Hubei , China
Tel:86-27-84492310
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