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White Powder 99% Pregabalin Active Pharmaceutical Ingredient CAS 148553-50-8

White Powder 99% Pregabalin Active Pharmaceutical Ingredient CAS 148553-50-8

  • White Powder 99% Pregabalin Active Pharmaceutical Ingredient CAS 148553-50-8
  • White Powder 99% Pregabalin Active Pharmaceutical Ingredient CAS 148553-50-8
White Powder 99% Pregabalin Active Pharmaceutical Ingredient CAS 148553-50-8
Product Details:
Place of Origin: China
Brand Name: VANZ
Certification: ISO9001
Model Number: PREGABALIN
Payment & Shipping Terms:
Minimum Order Quantity: 100g
Price: USD0.35- 0.7 Per Gram
Packaging Details: Aluminum foil bags or drum
Delivery Time: 3-5 days
Payment Terms: T/T, Western Union, MoneyGram
Supply Ability: 200kg per month
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Detailed Product Description
Name: Pregabalin CAS: 148553-50-8
Molecular Formula: C8H17NO2 Molecular Weight: 159.23
Test Method: HPLC Ppearance: White Powder
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White Powder 99% Pregabalin Active Pharmaceutical Ingredient CAS 148553-50-8

 

Introduction

 

Pregabalin (PGB, PGL, PGN), is a medication used to treat epilepsy, neuropathic pain, fibromyalgia, and generalized anxiety disorder. Its use for epilepsy is as an add-on therapy for partial seizures with or without secondary generalization in adults. Some off-label uses of pregabalin include restless leg syndrome, prevention of migraines, social anxiety disorder,and alcohol withdrawal. When used before surgery it does not appear to affect pain after surgery but may decrease the use of opioids. 

 

Basic Information

 

Product Name Pregabalin
CAS No. 148553-50-8
Molecular Formula C8H17NO2
Molecular Weight 159.23
Speicification 99% Min
Test Method HPLC
Appearance Powder
Odor & Taste Characteristic
Supplier Vanz
Storage
Store in cool & dry placc,away from strong light and heat
Shelf life
24 months when properly stored.

 

Side Effects

 

Sleepiness, confusion, trouble with memory, poor coordination, dry mouth, problem with vision, and weight gain. Potentially serious side effects include angioedema, drug misuse, and an increased suicide risk. When pregabalin is taken at high doses over a long period of time, addiction may occur, but if taken at usual doses the risk of addiction is low. It is classified as a GABA analogue and gabapentinoid.

 

History 

  • Pregabalin was synthesized in 1990 as an anticonvulsant. It was invented by medicinal chemist Richard Bruce Silverman atNorthwestern University in Chicago, Illinois.
  •  Silverman is best known for identifying the drug pregabalin as a possible treatment for epileptic seizures.
  •  During 1988 to 1990, Ryszard Andruszkiewicz, a visiting research fellow, synthesized a series of molecules for Silverman. One looked particularly promising.
  • The molecule was effectively shaped for transportation into the brain, where it activated L-Glutamic acid decarboxylase, an enzyme. neurotransmitter GABA and block convulsions.Eventually, the set of molecules were sent to Parke-Davis Pharmaceuticals for testing.
  • The drug was approved in the European Union in 2004.
  • The US received FDAapproval for use in treating epilepsy, diabetic neuropathic pain, and postherpetic neuralgia in December 2004.
  • Pregabalin then appeared on the US market under the brand name Lyrica in fall of 2005

 

Related Porducts

 

Tofacitinib Citrate CAS# 540737-29-9
Posaconazole CAS# 171228-49-2
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Sofosbuvir CAS# 1190307-88-0
Daclatasvir Dihydrochloride CAS# 1009119-65-6
Ledipasvir GS588 CAS# 1256388-51-8
Asunaprevir CAS# 630421-48-6
Vorapaxar CAS# 618385-01-6
Vildagliptin CAS# 274901-16-5

 

  • White Powder 99% Pregabalin Active Pharmaceutical Ingredient CAS 148553-50-8 0

Contact Details
Hubei Vanz Pharm Co.,ltd

Contact Person: Ms. Wendy Wang

Tel: +86 15927784577

Fax: 86-27-84492310

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Room 2114, Jingkai future town, Longyang Road, Wuhan Economic & Technological Development District, Wuhan City, Hubei , China
Tel:86-27-84492310
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