Peptides Pharm Raw Materials Endocrine System Hormones CAS 25126-32-3

Peptides Pharm Raw Materials Endocrine System Hormones CAS 25126-32-3

Sincalide is a cholecystokinetic drug administered by injection to aid in diagnosing disorders of the gallbladder and pancreas. It is the 8-amino acid C-terminal fragment of cholecystokinin, and also known as CCK-8

Uses and Functions:

1. Common adverse effects following administration include abdominal discomfort and nausea. These effects are more pronounced following rapid infusion.

2. Sincalide may be used to stimulate gallbladder contraction, as may be assessed by contrast agent cholecystography or ultrasonography, or to obtain by duodenal aspiration a sample of concentrated bile for analysis of cholesterol, bile salts, phospholipids, and crystals. It can also be used to stimulate pancreatic secretion (especially in conjunction with secretin) prior to obtaining a duodenal aspirate for analysis of enzyme activity, composition, and cytology.

3.In some instances it is used to accelerate the transit of a barium meal through the small bowel, thereby decreasing the time and-extent of radiation associated with fluoroscopy and x-ray examination of the intestinal tract.

Specification

Product Name:	Sincalide
Synonyms:	H-ASP-TYR(SO3H)-MET-GLY-TRP-MET-ASP-PHE-NH2;H-ASP-TYR(SO3H)-MET-GLY-TRP-MET-ASP-PHE-NH2 AMMONIUM SALT;CHOLECYSTOKININ [TYR(SO3H)27]-FRAGMENT 26-33 AMIDE;CHOLECYSTOKININ, OCTAPEPTIDE (26-33), SULFATED;CHOLECYSTOKININ OCTAPEPTIDE (SULFATED);CHOLECYSTOKININ OCTAPEPTIDE (SULFATED) AMMONIUM SALT;CHOLECYSTOKININ-8 (26-33), HUMAN, SULPHATED AMIDE;CHOLECYSTOKININ FRAGMENT 26-33 SULFATED
CAS:	25126-32-3
MF:	C49H62N10O16S3
MW:	1143.27
EINECS:	246-639-0
Product Categories:	Peptide;Cholecystokinin (CCK) receptor;Peptide Receptors;API;hormones
Purity:	98%,99%

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