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Strontium Ranelate Active Pharmaceutical Ingredient Terbinafine HCL CAS 135459-87-9
Strontium ranelate, a strontium(II) salt of ranelic acid, is a medication for osteoporosis marketed as Protelos or Protos by Servier. Studies indicate it can also slow the course of osteoarthritis of the knee. The drug is unusual in that it both increases deposition of new bone by osteoblasts and reduces the resorption of bone by osteoclasts. It is therefore promoted as a "dual action bone agent" (DABA).
|Product Name||Strontium ranelate|
|Synonyms||5-[bis(carboxymethyl)amino]-2-carboxy-4-cyano-3-thiopheneacetic acid strontium salt (1:2)|
|Packing||100G;500G;1Kg;25Kg(Export worthy packing)|
|Remark||For more details,please contact us|
Strontium ranelate is registered as a prescription drug in more than 70 countries for the treatment of post-menopausal osteoporosis to reduce the risk of vertebral and hip fractures. In the United Kingdom, strontium ranelate is prescribed under the National Health Service as a medicine for the treatment of post menopausal osteoporosis.
Strontium ranelate shows anti-fracture efficacy in very old elderly and osteopenic patients.
For 1% cream:
|Appearance||Off-white or primrose yellow crystalline powder|
|The spectrofram of the test solution corrsrponds to that of reference|
|The retention time of the major peak of the test solution corresponds to that of the RS|
|Turbidity of solution||Not more opalescent that reference solution class 1|
|Color of solution||Not more intensely colored that reference solution Y2|
|Loss of dying||20.0-23.5%|
|Chlorides||No more than 0.1%|
|Heavy metals(as Pb)||No more than 20ppm|
|Arsenic||No more than 0.0002%|
|Related substances(HPLC)||Any impurity NMT0.2%|
|Total impurities NMT0.5%|
|Solubility||Solute in 0.1mol/ hydrochloric acid solution, cery slightly solute in water, practically solute in methanol or acetate|
|Assay(on dried basisi)||Over 99.0%|
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