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Strontium Ranelate Active Pharmaceutical Ingredient Terbinafine HCL CAS 135459-87-9

Good quality Pharmaceutical Intermediates for sales
Good quality Pharmaceutical Intermediates for sales
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Strontium Ranelate Active Pharmaceutical Ingredient Terbinafine HCL CAS 135459-87-9

China Strontium Ranelate Active Pharmaceutical Ingredient Terbinafine HCL CAS 135459-87-9 supplier
Strontium Ranelate Active Pharmaceutical Ingredient Terbinafine HCL CAS 135459-87-9 supplier Strontium Ranelate Active Pharmaceutical Ingredient Terbinafine HCL CAS 135459-87-9 supplier

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Product Details:

Place of Origin: China
Brand Name: vanz
Certification: ISO9001
Model Number: 135459-87-9

Payment & Shipping Terms:

Minimum Order Quantity: 1kg
Packaging Details: bags or drum
Delivery Time: 3-5 days
Payment Terms: T/T, Western Union, MoneyGram
Supply Ability: 200kg per month
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Detailed Product Description
Name: Terbinafine HCL CAS: 135459-87-9
Appearance: White Powder COA: Available
Assay: 99%min Stock: Available

Strontium Ranelate Active Pharmaceutical Ingredient Terbinafine HCL CAS 135459-87-9

 

Introduction

 

Strontium ranelate, a strontium(II) salt of ranelic acid, is a medication for osteoporosis marketed as Protelos or Protos by Servier. Studies indicate it can also slow the course of osteoarthritis of the knee. The drug is unusual in that it both increases deposition of new bone by osteoblasts and reduces the resorption of bone by osteoclasts. It is therefore promoted as a "dual action bone agent" (DABA).

 

Basic Information

 

Product Name Strontium ranelate
Synonyms 5-[bis(carboxymethyl)amino]-2-carboxy-4-cyano-3-thiopheneacetic acid strontium salt (1:2)
CAS NO. 135459-87-9
EINECS 135459-87-9
Molecular Formula C12H6N2O8SSr2
Molecular Weight 513.491
Specifications:
Standard Assay ≥99%
Appearance White powder
Test Method HPLC
Other information:
Packing 100G;500G;1Kg;25Kg(Export worthy packing)
Applications Osteoporosis Treatment
Status Commercials
Remark For more details,please contact us

 

Medical Uses

 

Strontium ranelate is registered as a prescription drug in more than 70 countries for the treatment of post-menopausal osteoporosis to reduce the risk of vertebral and hip fractures. In the United Kingdom, strontium ranelate is prescribed under the National Health Service as a medicine for the treatment of post menopausal osteoporosis.

 

  • 2 major phase III clinical studies, SOTI (Spinal Osteoporosis Therapeutic Intervention) and TROPOS (Treatment of Peripheral Osteoporosis), were started in 2000 to investigate the efficacy of strontium ranelate in reducing vertebral fractures and peripheral fractures, including hip fractures.
  • In the 3 years results, reported in 2004, strontium ranelate showed significant reduction in vertebral fractures with 41% and hip fractures with 36% compared with patients treated with placebo.
  • The efficacy was sustained in 5 years data. The 5 years data confirmed that strontium ranelate can reduce the vertebral fractures significantly no matter the risk factors of the osteoporotic women have. 

Strontium ranelate shows anti-fracture efficacy in very old elderly and osteopenic patients.

 

For 1% cream:

  • for adults and children 12 years and older:
    • wash the affected skin with soap and water and dry completely before applying
    • apply once a day to affected skin for 2 weeks or as directed by a doctor
    • wash hands after each use
  • children under 12 years: ask a doctor

 

COA

 

Appearance Off-white or primrose yellow crystalline powder
Identification Posive
  The spectrofram of the test solution corrsrponds to that of reference
  The retention time of the major peak of the test solution corresponds to that of the RS
Acidity 6.5-8.5
Turbidity of solution Not more opalescent that reference solution class 1
Color of solution Not more intensely colored that reference solution Y2
Loss of dying 20.0-23.5%
Chlorides No more than 0.1%
Heavy metals(as Pb) No more than 20ppm
Arsenic No more than 0.0002%
Strontium 32.0-35.0%
Related substances(HPLC) Any impurity NMT0.2%
  Total impurities NMT0.5%
Solubility Solute in 0.1mol/ hydrochloric acid solution, cery slightly solute in water, practically solute in methanol or acetate
Assay(on dried basisi) Over 99.0%

 

FAQ

 

Q1: Are you a manufacturer ?

A: Yes, our factory is located in Jiayu, Hubei,  our lab located in Wuhan. But we also do some trading business.

Q2: What`s your delivery

A: We send goods in 3 working day after receiving your payment by DHL, FEDEX, TNT, EMS, AIR OR SEA as you request.

Q3: What certificates and documents do you offer?

A: Some technical paperwork is available, such as COA, HNMR, HPLC, LC-MS etc.

Q4: Why should I choose you?

A: Factory supply with the most compatitive price and high quality!!!

Q5: Can I get best price from you?

A: Of course. We don't chase excessive profits and always try tp give best offer. If you are good at bargaining, you can also enjoy fun of bargaining. Just don't make it too hard!

Q6: How should I pay?

A: We accept all kinds of payment ways. such as alibaba trade asssurance, T/T, West Union, Money Gram.

Q7: Do you provide free sample?

A: We can provide free sample of some chemicals and you just need you to cover the delivery cost.

 

Strontium Ranelate Active Pharmaceutical Ingredient Terbinafine HCL CAS 135459-87-9

 

Contact Details
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Contact Person: Amy

Tel: +8613277095342

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