Payment & Shipping Terms:
|Name:||Acadesine||Other Names:||AICA Riboside; AICAR|
|Molecular Weight:||258.231||Appearance:||Tan Powder|
Acadesine AICA Riboside Organic Reactive Intermediates CAS 2627-69-2
Other names: AICA Riboside; AICAR
Molecular formula: C9H14N4O5
Molecular weight: 258.231
Melting point: 214-215ºC
Boiling point: 726.3ºC
Flash point: 393.1ºC
Solubility: soluble in water
Appearance: tan powder
Acadesine (AICA-riboside) is a purine nucleoside analog with anti-ischemic properties used for the prevention of adverse cardiovascular outcomes in patients undergoing coronary artery bypass graft (CABG) surgery.
Acadesine has been shown to induce cell death apoptosis selectively in B-cells taken from healthy subjects and patients with B-CLL, with little effect on T-cells. As T-cells have an important role in fighting infection, it is anticipated that patients treated with acadesine will have a reduced risk of serious infections compared to those on current chemotherapies
Mechanism of Action:
The mechanism by which acadesine selectively kills B-cells is not yet fully elucidated. The action of acadesine does not require the tumour suppressor protein p53 like other treatments. This is important, as p53 is often missing or defective in cancerous B-cells. Studies have shown acadesine activates AMPK and induces apoptosis in B-cell chronic lymphocytic leukemia cells but not in T lymphocytes.
Shipment & Storage:
|Storage||Closed in container at cool and dry place away from direct light.|
|Packing||Aluminum foil bag, plastic bag, cardboard drum, plastic or glass bottle, customize.|
|Specification||10g-25kg per packing unit|
|Shipment method||By courier, by air or by sea.|
More products we supply: (for further information please contact us)
|6358-53-8||Citrus Red 2||C18H16N2O3|
Q1: Are you a manufacturer?
A: Yes, We manufacture bulk products in our factory located in Jiayu, Hubei, and produce small quantity and customer synthesis products in our lab located in Wuhan.
Q2: Do you have stock?
A: We understand most customers prefer stock, so we'll try to keep stock for most products. However, for some rare products, we won't keep stock and it needs time to synthesize.
Q3: What certificates and documents do you offer?
A: Some technical paperwork is available, such as COA, HNMR, HPLC, LC-MS etc.
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A: Powerful technical support-come from our highly skilled & fully experienced staff, working in chemical industry for over 5 years, in average.
Strict quality control-comes form our sophisticated management system.
Professional and warm sales team-since we believe we can only win via our hard work in a competitive world
Quick response and excellent presale and after sale service-since we believe our customers deserve all the best service
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A: Of course. We don't chase excessive profits and always try tp give best offer. If you are good at bargaining, you can also enjoy fun of bargaining. Just don't make it too hard!
Q6: How should I pay?
A: We accept all kinds of payment ways. such as alibaba trade asssurance, T/T, West union, Paypal.
Q7: Do you provide free sample?
A: Yes, we can provide free sample if we have in stock, just need you to cover the delivery cost.