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Pharmaceutical Intermediates sitagliptin intermediate CAS 767340-03-4

Good quality Pharmaceutical Intermediates for sales
Good quality Pharmaceutical Intermediates for sales
I am very happy to cooperate with your company for nearly three years, thank you very attentive service, thank you for the excellent product quality.

—— Stephnie

You always have very fast delivery, very happy to cooperate with you. Thank you.

—— John

Very pleased to become your customer, and very happy for our cooperation, hope to be your long-term parter.

—— Sara

we received the package, very fast, the quality is very good, will continue to buy your products.

—— Luice

I have emailed you a couple times and they get returned as undeliverable. Yes. I am happy with the powders. thank you.

—— Bryan

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Pharmaceutical Intermediates sitagliptin intermediate CAS 767340-03-4

China Pharmaceutical Intermediates  sitagliptin intermediate CAS 767340-03-4 supplier
Pharmaceutical Intermediates  sitagliptin intermediate CAS 767340-03-4 supplier Pharmaceutical Intermediates  sitagliptin intermediate CAS 767340-03-4 supplier

Large Image :  Pharmaceutical Intermediates sitagliptin intermediate CAS 767340-03-4

Product Details:

Place of Origin: China
Brand Name: Vanz
Model Number: sitagliptin intermediate 2

Payment & Shipping Terms:

Minimum Order Quantity: As custom's requirment
Packaging Details: as custom's requirment
Delivery Time: within 7 working days
Payment Terms: T/T, Western Union, MoneyGram
Supply Ability: 20 kg per month
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Detailed Product Description
Color: Yellow Package: Drum
Purity: 99 Test: HPLC
Usage: Sitagliptin Intermediate MF: C16H13F6N5O
MW: 405.30 Storage Temperature: Refrigerator

HPLC 99 sitagliptin intermediate CAS 767340-03-4 Pharmaceutical Intermediates

 

Product Info :

Molecular Formula: C16H13F6N5O
CAS Registry Number:767340-03-4

 

About sitagliptin :


Saxagliptin has an inhibition constant Ki of 1.3 nM for DPP4 inhibition, which is 10-fold more potent than either vildagliptin or sitagliptin (another two DPP4 inhibitors) with Ki of 13 and 18 nM. In addition, Saxagliptin demonstrates greater specificity for DPP4 than for either the DPP8 or DPP9 enzymes (400- and 75- fold, respectively). The active metablite of saxagliptin is two-fold less potent than the parent. Both Saxagliptin and its metabolite are highly selective (>4000-fold) for the prevention of DPP4 compared with a range of other proteases (selectivity of sitagliptin and vildagliptin for DPP4 is >2600 and <250-fold, respectively, compared with DPP8 and DPP9). Saxagliptin reduces the degradation of the incretin hormone glucagon-like peptide-1, thereby enhancing its actions, and is associated with improved β-cell function and suppression of glucagon secretion.

 

sitagliptin Usage :
intended for use as an internal standard for the quantification of Sitagliptin by GC- or LC-mass spectrometry.

Usage:An intermediate of sitagliptin .

Packaging:
(1) 10g/100g/500g/1kg, packaged by Aluminum foil bag.
(2) Customized package.

Chemical Properties:

Molecular Structure  Pharmaceutical Intermediates  sitagliptin intermediate CAS 767340-03-4
Density

1.6 g/cm3

Boiling Point

555.1 °C at 760 mmHg

Melting Point

178-180°C

Flash Point

555.1 °C at 760 mmHg

Storage Temperature

Refrigerator

Refractive index

1.59

  
Safety Information:

 

hazard Codes Xi
Risk Statements 41
Safety Statements 26-39

 
 
Pharmaceutical Intermediates  sitagliptin intermediate CAS 767340-03-4Pharmaceutical Intermediates  sitagliptin intermediate CAS 767340-03-4


FAQ:
Q1: Are you a manufacturer?
A: Yes, We manufacture bulk products in our factory located in Jiayu, Hubei, and produce small quantity and customer synthesis products in our lab located in Wuhan.
Q2: Do you have stock?
A: We understand most customers prefer stock, so we'll try to keep stock for most products. However, for some rare products, we won't keep stock and it needs time to synthesize.
Q3: What certificates and documents do you offer?
A: Some technical paperwork is available, such as COA, HNMR, HPLC, LC-MS etc.
Q4: Why should I choose you?
A: Powerful technical support-come from our highly skilled & fully experienced staff, working in chemical industry for over 5 years, in average.
Strict quality control-comes form our sophisticated management system.
Professional and warm sales team-since we believe we can only win via our hard work in a competitive world
Quick response and excellent presale and after sale service-since we believe our customers deserve all the best service
Q5: Can I get best price from you?
A: Of course. We don't chase excessive profits and always try tp give best offer. If you are good at bargaining, you can also enjoy fun of bargaining. Just don't make it too hard!
Q6: How should I pay?
A: We accept all kinds of payment ways. such as alibaba trade asssurance, T/T, West union, Paypal.
Q7: Do you provide free sample?
A: Yes, we can provide free sample if we have in stock, just need you to cover the delivery cost.

Contact Details
Wuhan Vanz Pharm Inc.

Contact Person: Miriam

Tel: +8618071739296

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