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Ntitumor Activity Soybean Extract Natural Herbal Extracts Glycine Max
Product Name: Soybean Extract
Synonyms: Soybean Ext;Soy Bean P.E;Glycine max (L.) Merr;Glycinemax(L.)merr.P.E;Soybean Extract
1. estrogen-like effects
Soy isoflavones are a non-steroidal estrogen, a chemical structure similar to estrogen, instead of both estrogen and estrogen receptors, estrogen-like role to play; and can interfere with estrogen binding to the receptor, exhibit anti estrogen-like effect on the body's estrogen levels have a two-way adjustment, menopausal women appear to diminish estrogen-related diseases such as osteoporosis, atherosclerosis, elevated blood lipids have a certain preventive effect.
2. The anti-tumor effect
Soy isoflavones have anti-tumor significantly, particularly with hormone-related tumors, such as breast cancer, prostate cancer. Genista flavin can effectively block the process of angiogenesis, cut off the source of nutrients, and thus delay or prevent the disease become cancer tumors, while preventing free radical damage to DNA to reduce cancer, but also effectively suppressed leukemia, colon cancer, lung cancer, liver cancer and gastric cancer.
Soybean extract soy saponins can inhibit tumor growth, tumor cell DNA synthesis and cell transfer inhibition, kill tumor cells directly, destroying its surface features, especially on human leukemia cells have a strong DNA synthesis inhibition; while HIV virulence and infectivity has an inhibitory effect on the X- ray has a protective effect, so cancer patients radiotherapy and chemotherapy-induced side effects have a good resistance to the role, but also to strengthen the body's immune system.
Genistein and daidzein as the main active ingredient, and the antioxidant capacity of genistein flavin strongest inhibited rat liver microsomal lipid peroxides Fe3 + -ADP-NADPH system caused the formation, Ic50 respectively 1.8 × 10-4M and 6.0 × 10-4M. At the same time they are also on the A enzyme in mice caused by peroxidation and improve antioxidant enzyme activity decreased significantly inhibited. Genistein may also increase superoxide dismutase (SOD) production in vivo.
4. The role of the cardiovascular system
Soy isoflavones have lipid-lowering and anti-atherosclerotic effect: soy isoflavones can positively regulates LDL receptors, promoting cholesterol clearance; antioxidant properties can reduce LDL particles deposited in artery walls; genistein Sukhothai reduce basal fibroblast growth factor, inhibit the proliferation of vascular smooth muscle cells.
Soybean extract soy saponins can inhibit the oxidation of serum lipids, inhibit superoxide production, and can reduce serum cholesterol, has anti-lipid oxidation, reduce the role of lipid peroxidation, lipid peroxidation and can change system quality on the liver cell damage, inhibit platelet and fibrin protein reduction.
Soy isoflavones has been improved non-specific immune function.
6. anti-inflammatory effect
Genistein as tyrosine kinase inhibitors, can inhibit the formation of NO; can inhibit vascular permeability enhancing effect of vascular endothelial growth factor (VEGF) induced, inhibition of VEGF expression and release.
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