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|Apperance:||White Crystaline Powder||Purity:||99%min|
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Adenine Hydrochloride Hemihydrate Pharmaceutical Raw Materials CAS 6055-72-7
a nucleobase (a purine derivative). Its derivatives have a variety of roles in biochemistry including cellular respiration, in the form of both the energy-rich adenosine triphosphate (ATP) and the cofactors nicotinamide adenine dinucleotide (NAD) and flavin adenine dinucleotide (FAD). It also has functions in protein synthesis and as a chemical component of DNA andRNA.
The shape of adenine is complementary to either thymine in DNA or uracil in RNA.
The image right shows pure adenine, as an independent molecule. When connected into DNA, a covalent bond is formed between deoxyribose sugar and the bottom left nitrogen, so removing the hydrogen. The remaining structure is called an adenine residue, as part of a larger molecule. Adenosine is adenine reacted withribose as used in RNA and ATP; deoxyadenosine adenine attached to deoxyribose, as is used to form DNA.
|Name||Adenine hydrochloride hemihydrate|
|Synonyms||1H-Purin-6-amine monohydrochloride hydrate (2:1)|
|CAS Registry Number||6055-72-7|
Uses and Functions:
Adenine is one of the two purine nucleobases (the other being guanine) used in forming nucleotides of thenucleic acids. In DNA, adenine binds to thymine via two hydrogen bonds to assist in stabilizing the nucleic acid structures. In RNA, which is used for protein synthesis, adenine binds to uracil.
Adenine forms several tautomers, compounds that can be rapidly interconverted and are often considered equivalent. However, in isolated conditions, i.e. in an inert gas matrix and in the gas phase, mainly the 9H-adenine tautomer is found.
Purine metabolism involves the formation of adenine and guanine. Both adenine and guanine are derived from the nucleotide inosine monophosphate (IMP), which in turn is synthesized from a pre-existing ribose phosphate through a complex pathway using atoms from the amino acids glycine, glutamine, and aspartic acid, as well as the coenzyme tetrahydrofolate.
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|Storage||Store in a well-closed container away from moisture|
|Shelf Life||2 years if sealed and store away from direct sun light.|
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